Daniel S. Ory, MD
- Professor of Medicine, Cell Biology and Physiology
- Co-Director, BioMed21 Diabetic Cardiovascular Disease Center
Cholesterol homeostasis in cardiovascular and Niemann-Pick type C disease.
Atherosclerotic coronary artery disease is a major diabetes complication. Work in my laboratory focuses on identification and characterization of genes that function in the uptake, intracellular transport, and export of lipoprotein-derived cholesterol, and on gene programs that regulate cellular cholesterol balance. The goal of our research is to shed light on the molecular mechanisms involved in atherosclerotic lesion formation, and to identify biomarkers for early detection of vascular disease in diabetes.