The Center for Cardiovascular Research (CCR) at Washington University School of Medicine supports basic research laboratories that focus on understanding the biologic processes that are responsible for cardiovascular disease.
A major objective of the CCR is to establish novel interfaces among cardiovascular researchers in diverse scientific disciplines, including:
- Molecular and cellular biology
- Bioorganic chemistry
Accordingly, the CCR provides a unique research environment for scientists with distinct backgrounds who have common interests in diseases of the heart and vasculature. In addition, the CCR facilitates interactions between its basic scientists and clinical researchers engaged in patient-oriented research. The CCR also supports a cutting-edge Mouse Cardiovascular Phenotyping Core.
Current research efforts within the CCR include:
- Cellular ketone body metabolism
- The role of autophagy in atherosclerosis
- Cellular and molecular basis of heart failure
- Cellular responses to myocardial injury
- Mechanisms of cell death
- Genomic predictors of cardiovascular disease complications
The CCR supports the basic science research faculty members in the Cardiovascular Division and those with primary appointments in other departments throughout the University.
The Cardiovascular Division at Washington University School of Medicine is comprised of 75 faculty members highly renowned for their contributions to the basic, translational and clinical sciences. Outstanding clinical services are provided through the Division’s faculty and highly-competitive cardiovascular disease fellows.
Interdisciplinary research within the CCR is performed in collaboration with investigators from the following groups:
- Division of Bioorganic Chemistry
- Diabetic Cardiovascular Disease Center
- Cardiovascular Imaging Laboratory
- Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN)
- Center for Pharmacogenomics
- Center for the Investigation of Membrane Excitability Diseases
- Center for Cardiovascular Outcomes Research
One of the major goals of the CCR is to provide an exciting and scientifically rigorous training environment for graduate students, PhD, MD, and MD/PhD postdoctoral fellows and cardiology research fellows. The diverse strengths of the CCR and its affiliated investigators provide a unique training environment for students, fellows and junior faculty. Postdoctoral training in the CCR is supported by an NHLBI-sponsored T32 training grant that provides one to two years of research support. Research faculty, fellows and students meet twice weekly through popular CCR trainee and faculty (internal and visiting professor) seminar series.